This is one of the most common questions I’m asked at my clinic in Addlestone, usually by clients who are curious about Profhilo but want to understand exactly what they’re committing to before they book. The short answer is two sessions, spaced four weeks apart, for the initial course. But there’s quite a bit more worth understanding about why that is, what happens at each stage, and what to expect as your results develop over time.
The Standard Profhilo Course: Two Sessions, Four Weeks Apart
Profhilo is a bio-remodelling treatment rather than a filler. It works by spreading a high concentration of hyaluronic acid (64mg per syringe) beneath the skin’s surface, triggering the production of collagen and elastin over a period of weeks. Because this process takes time — your skin needs to respond biologically — a single session isn’t enough to achieve full results.
The standard protocol, developed by IBSA (the manufacturer of Profhilo), is two treatment sessions spaced four weeks apart. This interval gives the first session time to begin stimulating collagen and elastin production before the second session reinforces and builds on that response. Together, the two sessions produce the full bio-remodelling effect that Profhilo is known for.
What Happens After the First Session?
Within the first few days after your initial Profhilo treatment, most clients notice an improvement in hydration. The skin often looks more luminous and feels softer — this is the immediate hydrating effect of the hyaluronic acid beginning to work. Any small bumps or mild redness at the injection sites (from the BAP Technique’s ten injection points) typically settle within 24 to 48 hours.
Over the following two to three weeks, the deeper bio-remodelling process begins. Collagen and elastin fibres start to regenerate and reorganise within the skin tissue. You may notice your skin feeling firmer and more elastic, with a gradual improvement in texture and tone. These changes are subtle at this stage — the first session lays the foundation; the second builds on it.
What Happens After the Second Session?
The second session, four weeks after the first, delivers another dose of hyaluronic acid to the same areas using the BAP Technique. This reinforces the collagen and elastin stimulation already underway and completes the full bio-remodelling cycle.
Full results from the complete course are typically visible four to six weeks after the second session, once the tissue remodelling has had time to fully develop. At this point, most clients notice a significant improvement in skin firmness, hydration, texture, and overall radiance — without any change to their facial structure or volume.
How Long Do Results Last?
Results from a full Profhilo course typically last around six months. Some clients find their results last a little longer depending on their skin type, age, lifestyle, and how well they maintain their skin in the months following treatment.
To sustain the improvement, most clients return for a maintenance session every six to nine months. This single top-up session helps preserve the collagen and elastin stimulated during the initial course, keeping the skin in the improved state rather than allowing it to return to its pre-treatment baseline.
Is a Course of Three Sessions Better?
For most clients, two sessions is the recommended and clinically supported initial course. However, in some cases — particularly for clients with more advanced skin laxity, significant loss of elasticity, or mature skin — a third session may be beneficial.
At Precise Aesthetics, I always assess each client individually during a free consultation. If I feel a third session would meaningfully improve your outcome, I’ll discuss that with you and explain why, so you can make an informed decision. There’s no one-size-fits-all approach to aesthetics, and I won’t recommend additional treatments unless there’s a genuine reason for them.
Can You See Results After Just One Session?
Yes — particularly in terms of hydration and glow, many clients notice a visible improvement after the first session alone. However, the full structural benefit of Profhilo — the improvement in firmness, elasticity, and overall skin quality — requires both sessions to develop properly. Stopping after one session would be like completing only half the course; the results would be limited compared to the full outcome.
How Does Profhilo Compare to Other Skin Boosters?
Profhilo is often compared to other hyaluronic acid skin boosters such as Restylane Skinboosters or Juvederm Volite. While these treatments also improve hydration and skin quality, Profhilo’s NAHYCO technology produces a much higher concentration of pure hyaluronic acid without chemical cross-linking agents. This allows it to spread more freely beneath the skin and stimulate a more comprehensive bio-remodelling response.
In practice, many practitioners — including myself — find that Profhilo produces a more noticeable improvement in skin firmness and elasticity than traditional skin boosters, particularly when the full two-session course is completed.
If you’re also considering treatments for specific skin texture concerns or post-treatment glow, microneedling and polynucleotides are popular additions that complement Profhilo well. Many of my clients at Precise Aesthetics combine these treatments for a more comprehensive result.
What About Profhilo for the Neck, Décolletage, or Hands?
Profhilo can be used on areas beyond the face — including the neck, décolletage, hands, arms, and knees — all of which tend to show signs of ageing earlier than clients expect. The treatment protocol for these areas follows the same principle: two sessions spaced four weeks apart, with maintenance every six to nine months.
Some clients combine face and neck treatment in the same session. This is something I can discuss with you at consultation, as it depends on the amount of product used and your specific concerns.
Frequently Asked Questions
How many Profhilo sessions do you need for the face?
The standard course for the face is two sessions, spaced four weeks apart. Full results develop four to six weeks after the second session as collagen and elastin production matures. Maintenance sessions every six to nine months help sustain the result.
How soon will I see results from Profhilo?
Many clients notice improved hydration and a healthy glow within a few days of the first session. Firmer, smoother skin with improved elasticity develops gradually over the following weeks, with full results visible four to six weeks after the second session.
Can I have more than two Profhilo sessions?
Yes. Some clients with more advanced skin laxity benefit from a third session, completed four weeks after the second. Your practitioner will advise whether this is appropriate based on your skin assessment and the results from your initial course.
How often should I have Profhilo after the initial course?
Most clients return for a maintenance session every six to nine months. This sustains the collagen and elastin stimulated during the initial course. Your practitioner will recommend a schedule based on how your skin responds.
Is Profhilo worth it for one session only?
One session will produce some improvement in hydration and glow, but it won’t deliver the full bio-remodelling effect that makes Profhilo distinctive. Two sessions are needed for the collagen and elastin stimulation to develop fully. Most clients find the two-session course well worth the investment once they see their results.
How long does a Profhilo session take?
Each Profhilo session takes around 15 to 30 minutes, including preparation and the BAP Technique injections. The treatment itself is quick and requires no significant recovery time — most clients return to their normal routine the same day.
Book Your Profhilo Consultation in Addlestone, Surrey
If you’d like to find out whether Profhilo is the right treatment for your skin, I offer free consultations at Precise Aesthetics in Addlestone. During your consultation, I’ll assess your skin, discuss your concerns and goals, and recommend a treatment plan tailored to you — with no pressure and no obligation.
The clinic is easily accessible from Weybridge, Chertsey, Woking, and the surrounding Surrey areas, with free off-road parking available for all clients.
You can find out more about Profhilo at Precise Aesthetics or book your free consultation online.
Injectable aesthetic treatments in the UK are regulated by the MHRA. Always ensure your practitioner is qualified, insured, and using licensed products.